delibae/claude-prism

An offline-first scientific writing workspace powered by Claude. LaTeX + Python + 100+ scientific skills all running locally.

What it solves

ClaudePrism is a local-first scientific writing workspace that combines LaTeX, Python, and AI assistance. It removes the need to upload all files to a cloud-based workspace while providing integrated tools for scientific research, data analysis, and document compilation.

How it works

The application is a native desktop app built with Tauri 2 and Rust. It integrates Tectonic for offline LaTeX compilation and the uv package manager for one-click Python virtual environment setup. Users can interact with Claude (via Anthropic's API) to generate content, run analysis scripts, and manage documents. It also includes a Git-based history system for version control and a live PDF preview with SyncTeX support.

Who it’s for

Researchers, scientists, and academics who write scientific papers, theses, or posters and need a tightly integrated environment for LaTeX, Python-based data analysis, and AI-assisted writing.

Highlights

  • Integrated Python Environment: Uses uv to quickly set up project-level virtual environments for data processing and plotting.
  • 100+ Scientific Skills: Access to curated prompts and tool configurations for specialized fields like bioinformatics, cheminformatics, and machine learning.
  • Offline LaTeX: Embedded Tectonic allows for offline compilation without requiring a full TeX Live installation.
  • Capture & Ask: A tool to select regions of a PDF and immediately ask the AI about specific equations or figures.
  • Git-based History: Local snapshots and visual diffs for tracking changes and accepting/rejecting AI-proposed edits.
  • Zotero Integration: OAuth-based bibliography and citation management.

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